Radicals and antioxidants updating a personal view


10-May-2016 03:16

A free radical (FR) is an atom or molecule that contains an unpaired electron in its outer orbital.This situation confers them instability and the need to lose/gain an electron in order to get stable.All these oxidative and AOX activities can be assayed on various ophthalmological samples, including aqueous humor, vitreous body, and tear biopsies, and in the blood, urine, or saliva.Comparing the results of determinations of oxidative and AOX status may reflect the balance between them and the degree of OS by laboratory tests performed in samples from our ophthalmic patients.

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Among them, lipids are probably the most susceptible to undergo oxidation.OS has also been implicated in ophthalmic processes, including ocular surface disorders, cataracts, glaucoma, diabetic retinopathy (DR), retinitis pigmentosa, toxic neuropathies, uveitis, and age-related macular degeneration (AMD).



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